The Islamic Society of Central New York (ISCN) was founded in 1981. According to Omar Khalidi, the mosque building in Syracuse's University Hill neighborhood was constructed from 1978-1981 by local architect James Ruddock.
It is a one-story building, faced in concrete and stucco, with a minaret on the western (street-facing) facade. The main entrance to the mosque is at the northwestern corner, through an ogee arch entrance portal.
In 2007, the ISCN bought 46 acres of property in the neighboring town of Onondaga, and in 2014 submitted plans to build a 27,000 sq. ft. mosque and community center on the property. This facility would not replace the Syracuse mosque, but would serve as an additional space for the growing Muslim community. The proposed center would be built in 3 parts: first a prayer space and restrooms; then a lobby and expansion of the mezzanine; and finally a community hall. As of 2014, the ISCN was going through the town approval process and raising funds.